Alternate Fluctuations of Leucine and Thymidine Incorporation by Mammary Tumors in Rats during the Estrous Cycle1
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چکیده
tissue mitotic counts, which also peaked at diestrus 1. Radioactivities in the acid-soluble fraction of the incubated tissues were not significantly different for either labeled precursors throughout the estrous cycle. Autoradiographic studies of tissues collected after incubation with [3H]thymidine showed that silver grains were localized over cell nuclei. The data indicate that the growth of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats during the estrous cycle is associated with a peak of [3H]leucine incorporation at proestrus and a wave of [3H]thymidine incorporation during metestrus-diestrus.
منابع مشابه
Alternate fluctuations of leucine and thymidine incorporation by mammary tumors in rats during the estrous cycle.
tissue mitotic counts, which also peaked at diestrus 1. Radioactivities in the acid-soluble fraction of the incubated tissues were not significantly different for either labeled precursors throughout the estrous cycle. Autoradiographic studies of tissues collected after incubation with [3H]thymidine showed that silver grains were localized over cell nuclei. The data indicate that the growth of ...
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